产品货号：
Z19700
中文名称：
MAOA抗体
英文名称：
Anti-MAOA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MAOA Antibody |
| 指标别名 | MAO A;MAOA;monoamine oxidase A;Monoamine oxidase type A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ICC/IF |
| 基因名称 | MAOA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MAOA (457-493aa REVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWER),different from the related mouse sequence by five amino acids,and from the related rat sequence by six amino acids. |
| 实际分子量 | 60KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MAOA(Monoamine oxidase A),also known as AMINE OXIDASE (FLAVIN-CONTAINING) A,is an enzyme that in humans is encoded by the MAO-A gene.MAOA is an isozyme of monoamine oxidase which is also mapped on Xp11.3.MAOA degrades amine neurotransmitters,such as dopamine,norepinephrine,and serotonin.The protein localizes to the outer mitochondrial membrane.Mutation in MAOA results in monoamine oxidase deficiency,or Brunner syndrome.In humans,there is a 30-base repeat sequence repeated in one of several different numbers of times in the promoter region of the gene coding for MAOA.MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder.Inhibition of MAOA prevented apoptosis,and serum starvation of cortical brain cells from Maoa-deficient mice resulted in reduced apoptosis compared with wildtype mice. |
| Uniprot ID | P21397 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | monoamine oxidase A |
| 蛋白名全称 | Amine oxidase [flavin-containing] A |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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